His parents work at opposite ends of the country, (= a long distance apart) so they only see each other at weekends.

他的父母在这个国家相距很远的两个地方工作，因此只能周末见面。

the opposite sex

异性

in the opposite direction

向反方向

I thought this medicine would make me sleep, but it had the opposite effect.

我以为这种药能让我睡着，但效果却恰恰相反。

The hotel is only 5 blocks away opposite the bank.

那家宾馆离这里只有5个街区，在银行的对面。

Long is the opposite of short.

长是短的反义词。

I didn’t feel sleepy at all — just the opposite, in fact.

我一点儿都不困，事实上正好相反。