extreme cold / poverty

极其寒冷/赤贫

The suffering of the people was extreme.

人们遭受的灾难极为深重。

extreme weather

极端天气

the extreme north of China

中国的最北端

go / run to extremes

走极端

extremes of cold / rain

严寒/骤雨

He used to be shy, but now he's gone / run to the opposite extreme.

他以前很腼腆，现在却走向了另一个极端。